The looted top-seeded Duke Blue Devils will face the second-seeded Louisville Cardinals for Saturday’s 2025 ACC Tournament Championship. Duke postponed a ferocious rally from North Carolina 74-71, which was the fifth seeded in the semifinals on Friday night, with Louisville beating Clemson 76-73. The Cardinals (27-6, 18-2 ACC), who won 11 in 21 of their 22 games, are 2-4 against ranked teams this season. The Blue Devils (30-3, 19-1 ACC) without freshman forward Cooper Flag (ankles) won 10 consecutive wins and 26 of their 27 games.
Tip-offs from the Spectrum Center in Charlotte, North Carolina are set at 8:30pm ET. Duke defeated Louisville 76-65 in the only meeting during the regular season on December 8th. Duke is a 6.5-point favorite on the Sportsline Consensus’ latest Louisville vs Duke odds. Before you create a Duke vs. Louisville pick, check out the predictions of college basketball from the sports line projection model.
This model simulates all Division 1 college basketball games 10,000 times. Enter Conference Championship Week with a 225-165 betting roll (+1873) with all the best college basketball picks dating back to 2023. Anyone who follows the sportsbook or betting app may have seen a big return.
Now the model is aiming at Louisville vs. Duke and you can now access the Sports Line and see the picks. Here are the Duke vs Louisville college basketball lines and trends:
Duke vs. Louisville Spread: Duke-6.5
Duke vs. Louisville Over/Under: 147.5 Points Duke vs. Louisville Money Line: Duke-254, Louisville +206lou: The Cardinals are 6-4 against the spread of the last 10 games.
Why do you need to back the duke
Flag came out indefinitely, and Blue Devils turned to freshman guard Kon Knueppel for offensive stability. In his semi-final victory over Arch Rival North Carolina on Friday, Knupel finished with 17 points, four rebounds and three assists. He poured 28 points and grabbed eight assists and five rebounds in a 78-70 win over Georgia Tech in quarterfinals on Thursday. With 29.9 minutes per game, he averages 14.2 points, 3.9 rebounds, 2.7 assists and one steal.
Junior guard Tyrees Proctor is one of three Blue Devils who averaged double-digit scores in the season. With 29.2 minutes per game, he averages 11.8 points, 3.2 rebounds and 2.2 assists. He scored 11 points and added three rebounds and two steals in the semi-final against the Tar Heels. He made a 82-69 victory over North Carolina on March 8th, pouring in 16 points and adding two rebounds. Check out the teams you choose here.
Why should I go back to Louisville?
Senior guard Chucky Hepburn supports the power of the Cardinals. After spending the last three years at Wisconsin, the transfer in his first season with the program averages 16.4 points, 5.9 assists, 3.5 rebounds and 2.4 steel in 34.3 minutes. He has scored 12 points, five assists, five restores and six steals in the semi-finals at Clemson on Friday. He scored 20 points, eight assists and two rebounds in a 75-73 victory over Stanford in the quarterfinals on Thursday.
Senior guard Terrence Edwards Jr. is one of four Louisville players who average double digits score. With 32.2 minutes per game, he averages 16.1 points, 3.9 rebounds and 2.6 assists. He poured in 21 points, grabbed eight rebounds and gave three assists in Friday’s victory over the Tigers. In the quarter-finals against Stanford, he scored 25 points, adding two rebounds and two assists. Check out the teams you choose here.
How to make a Duke vs. Louisville pick
Sportsline’s model projects a total of 149 points. It also says that one side of the spread will hit at over 60% of the simulation. You can only get picks on the Sports Line.
So which side of the spread won Louisville vs Duke and hit the 60% or more of the simulation? Go to the Sports Line and see which side of the spread is jumping. Everything is from an advanced model that has grown nearly $1,900 on college basketball picks dating back to 2023.
